Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-{[3-(4-Chlorophenyl)propyl]amino}benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | Ethyl 4-{[3-(4-chlorophenyl)propyl]amino}benzoate | HCID 13079692 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-{[3-(4-Chlorophenyl)propyl]amino}benzoic acid | HCID 13079691 | — |
반응 단계
A mixture of 16.3 g. of ethyl 4-[3-(p-chlorophenyl)propylamino]benzoate, 16.3 g. of potassium hydroxide and 200 ml. of 95% ethanol is refluxed for 3 hours. The mixture is diluted with 100 ml. of water brought to pH 6 with concentrated hydrochloric acid. Chilling and filtering gave 15 g. of white crystals. Recrystallization from ethanol gave 8.6 g. of white crystals, m.p. 191°-192° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04185115 |
| 출처 데이터셋 | uspto-grants-1980_01 |
| ORD ID | ord-827cf6daf3cb43fdb27a1921f706f6e7 |
| 출처 메모 | uspto-grants-1980_01 |