Water → benzenesulfonamide, n-2-pyridinyl-

HRID 2052542

반응식

HRID 2052542 반응식
[S:1](Cl)([OH:4])(=O)=[O:2].[CH:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[NH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=1.O>O1CCCC1>[C:6]1([S:1]([NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)(=[O:4])=[O:2])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 104392-AminopyridineHCID 22564087Benzene sulphochloride

생성물 1

HCID 261514benzenesulfonamide, n-2-pyridinyl-

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

A solution of 264 g of benzene sulphochloride was added dropwise at 10° to 25° C. to a solution of 282 g of 2-aminopyridine in 1200 ml of tetrahydrofuran. After two hours continuous stirring without further cooling, the mixture was poured into water. The reaction product was suction filtered and washed first with water and then with methanol.

후처리

  1. filtrationfiltered
  2. washwashed first with water

출처 및 근거

ORD 기록
ord-3eeb4aaf21c44523984185ff1c34f48c
출처 데이터셋
uspto-grants-1980_01
특허 번호
US04186019

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