Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(3-Chlorophenyl)furan-2-carboxylic acid → 5-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-1H-indole-2-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(3-Chlorophenyl)furan-2-carboxylic acid | HCID 736256 | — |
| 반응물 | Ethyl 5-amino-1H-indole-2-carboxylate | HCID 10726872 | — |
| 생성물 | 5-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-1H-indole-2-carboxylic acid ethyl ester | HCID 59654633 | — |
반응 단계
5-(3-Chloro-phenyl)-furan-2-carboxylic acid (65) (54 mg, 0.24 mmol) was coupled to ethyl ester (58) (50 mg, 0.24 mmol) using Method C. The crude residue was purified by column chromatography eluting with 20% EtOAc in heptane to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07326732B2 |
| 출처 데이터셋 | uspto-grants-2008_02 |
| ORD ID | ord-a4a0c2e2cc1b4c928b3665909ce4d6e5 |
| 출처 메모 | uspto-grants-2008_02 |