5-Phenylfuran-2-carboxylic acid → 5-Phenyl-furan-2-carboxylic acid [3-(2-cyano-vinyl)-phenyl]-amide

HRID 2053197

반응식

HRID 2053197 반응식
[C:1]1([C:7]2[O:11][C:10]([C:12]([OH:14])=O)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:15][C:16]1[CH:17]=[C:18]([CH:22]=[CH:23][C:24]#[N:25])[CH:19]=[CH:20][CH:21]=1>>[C:24]([CH:23]=[CH:22][C:18]1[CH:17]=[C:16]([NH:15][C:12]([C:10]2[O:11][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[CH:8][CH:9]=2)=[O:14])[CH:21]=[CH:20][CH:19]=1)#[N:25]

참가 물질

3

반응물 2

HCID 7362555-Phenylfuran-2-carboxylic acidHCID 534254963-(3-Amino-phenyl)-acrylonitrile

생성물 1

HCID 723488125-Phenyl-furan-2-carboxylic acid [3-(2-cyano-vinyl)-phenyl]-amide

실험 절차

Carboxylic acid (56) (120 mg, 0.64 mmol) was coupled to aniline (88) (92 mg, 0.64 mmol), using Method C to give the title compound.

출처 및 근거

ORD 기록
ord-7bc9a4ea41f3485492a8a44225a6493f
출처 데이터셋
uspto-grants-2008_02
특허 번호
US07326732B2

연결된 노트

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