3-Aminocinnamic acid ethyl ester → 3-{3-[(6-Bromo-pyridine-2-carbonyl)-amino]-phenyl}-acrylic acid ethyl ester

HRID 2053217

반응식

HRID 2053217 반응식
[Br:1][C:2]1[N:7]=[C:6]([C:8]([OH:10])=O)[CH:5]=[CH:4][CH:3]=1.[CH2:11]([O:13][C:14](=[O:24])[CH:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH2:23])[CH:18]=1)[CH3:12]>>[CH2:11]([O:13][C:14](=[O:24])[CH:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH:23][C:8]([C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([Br:1])[N:7]=2)=[O:10])[CH:18]=1)[CH3:12]

참가 물질

3

반응물 2

HCID 978253-Aminocinnamic acid ethyl esterHCID 5939196-Bromopyridine-2-carboxylic acid

생성물 1

HCID 723488093-{3-[(6-Bromo-pyridine-2-carbonyl)-amino]-phenyl}-acrylic acid ethyl ester

실험 절차

6-Bromo-pyridine-2-carboxylic acid (127 mg, 0.63 mmol) was coupled to aniline (60)(120 mg, 0.63 mmol) using Method C to give the title compound.

출처 및 근거

ORD 기록
ord-1d87fa4f79604e20b4c509c40defe302
출처 데이터셋
uspto-grants-2008_02
특허 번호
US07326732B2

연결된 노트

불러오는 중…