1-Benzyl-3-methyl-4-piperidone → 1-Benzyl-3-methyl-4-hydroxy-4-(4-trifluoromethylbenzofur-7-yl)piperidine

반응식

[CH2:15]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[N:22]1[CH2:23][CH:24]([CH3:29])[C:25](=[O:28])[CH2:26][CH2:27]1.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([Br:12])[c:7]2[c:8]1[cH:9][cH:10][o:11]2)([F:13])[F:14]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:25]2([OH:28])[CH:24]([CH3:29])[CH2:23][N:22]([CH2:15][c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[CH2:27][CH2:26]2)[c:7]2[c:8]1[cH:9][cH:10][o:11]2)([F:13])[F:14]

참가 물질

반응물 2

HCID 5609651-Benzyl-3-methyl-4-piperidone

HCID 121147077-Bromo-4-(trifluoromethyl)benzofuran

생성물 1

HCID 224956381-Benzyl-3-methyl-4-hydroxy-4-(4-trifluoromethylbenzofur-7-yl)piperidine

출처 및 근거

ORD 기록: ord-cf7dfa9310c546d3879d1a60526d4230
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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