(2-Methyl-1,3-thiazol-4-yl)acetic acid → HCID 59654967, 화합물

반응식

[CH3:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([OH:10])=O)[N:6]=1.[NH2:11][C:12]1[CH:19]=[CH:18][C:15]([C:16]#[N:17])=[CH:14][C:13]=1[C:20](=O)[C:21]1[CH:26]=[CH:25][C:24]([CH2:27][CH3:28])=[CH:23][CH:22]=1>>[CH2:27]([C:24]1[CH:23]=[CH:22][C:21]([C:20]2[C:13]3[C:12](=[CH:19][CH:18]=[C:15]([C:16]#[N:17])[CH:14]=3)[NH:11][C:8](=[O:10])[C:7]=2[C:5]2[N:6]=[C:2]([CH3:1])[S:3][CH:4]=2)=[CH:26][CH:25]=1)[CH3:28]

참가 물질

반응물 2

HCID 854632(2-Methyl-1,3-thiazol-4-yl)acetic acid

HCID 69216568HCID 69216568, 화합물

생성물 1

HCID 59654967HCID 59654967, 화합물수율 27%

실험 절차

Synthesized from (2-methyl-thiazol-4-yl)-acetic acid and 4-Amino-3-(4-ethyl-benzoyl)-benzonitrile according to general procedure 2. Yield 27%.

출처 및 근거

ORD 기록: ord-a16002984d224c90808f1b673f95c257
출처 데이터셋: uspto-grants-2008_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07326788B2

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