4-Chloro-3-methylaniline → HCID 71127758, 화합물

반응식

[Cl:1]C1C=CC(N)=CC=1C.[Br:10][C:11]1[CH:16]=[C:15](C)[C:14]([CH3:18])=[CH:13][C:12]=1[N:19](C(C)C)[C:20]([CH:22]1[CH2:27][CH2:26][N:25]([C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[CH2:24][CH2:23]1)=[O:21]>>[Br:10][C:11]1[CH:16]=[C:15]([Cl:1])[C:14]([CH3:18])=[CH:13][C:12]=1[NH:19][C:20]([CH:22]1[CH2:27][CH2:26][N:25]([C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[CH2:24][CH2:23]1)=[O:21]

참가 물질

반응물 2

HCID 235364-Chloro-3-methylaniline

HCID 59134773HCID 59134773, 화합물

생성물 1

HCID 71127758HCID 71127758, 화합물

실험 절차

Tert-butyl 4-{[(2-bromo-4-chloro-5-methylphenyl)amino]carbonyl}-piperidine-1-carboxylate 2-5 was prepared from 4-chloro-3-methylaniline 2-1 following a similar procedure to that described for 4-{[(2-bromo-4,5 dimethylphenyl)(isopropyl)amino]carbonyl}piperidine-1-carboxylate 1-12.

출처 및 근거

ORD 기록: ord-9b5ef35128b147d7999cbb93c113c041
출처 데이터셋: uspto-grants-2008_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07329673B2

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