3-Chloro-4-methoxybenzoyl chloride → 1-Cyclopropyl-4-[5-(3-chloro-4-methoxyphenyl)[1,2,4]oxadiazol-3-yl]piperidine

HRID 2055700노트

반응식

HRID 2055700 반응식
[CH:1]1([N:4]2[CH2:9][CH2:8][CH:7]([C:10]([NH:12][OH:13])=[NH:11])[CH2:6][CH2:5]2)[CH2:3][CH2:2]1.[Cl:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][C:23]=1[O:24][CH3:25])[C:18](Cl)=O>>[CH:1]1([N:4]2[CH2:9][CH2:8][CH:7]([C:10]3[N:11]=[C:18]([C:17]4[CH:21]=[CH:22][C:23]([O:24][CH3:25])=[C:15]([Cl:14])[CH:16]=4)[O:13][N:12]=3)[CH2:6][CH2:5]2)[CH2:2][CH2:3]1

참가 물질

3

반응물 2

HCID 47692993-Chloro-4-methoxybenzoyl chlorideHCID 178513372HCID 178513372, 화합물

생성물 1

HCID 596577671-Cyclopropyl-4-[5-(3-chloro-4-methoxyphenyl)[1,2,4]oxadiazol-3-yl]piperidine

실험 절차

The title compound was prepared by a similar procedure to that described in Example 35a, starting from 1-cyclopropyl-N-hydroxypiperidine-4-carboxamidine and 3-chloro-4-methoxybenzoyl chloride.

출처 및 근거

ORD 기록
ord-c5b489dbee2b4267800822acf1964a9a
출처 데이터셋
uspto-grants-2008_02
특허 번호
US07332508B2

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