참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 4,6,6,6-Tetrachloro-2-cyano-3,3-dimethylhexanoic acid | HCID 20434843 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane-1-carbonitrile | HCID 12898173 | 79% |
반응 단계
4-Chloro-2-cyano-3,3-dimethyl-6,6,6-trichlorohexanoic acid (40 g) was dissolved in dimethyl formamide (66 ml) and the solution, at room temperature, was saturated with gaseous ammonia with no external cooling. The solution was stirred at 140° C. for 5 hours, then diluted with water and extracted with ether (3×100 ml). The ether solution was washed with saturated NaCl, dried over MgSO4 and evaporated to afford Compound A as a yellow oil (purity 85%) which partly crystallized on standing. Yield 79%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04211720 |
|---|
| 출처 데이터셋 | uspto-grants-1980_07 |
|---|
| ORD ID | ord-bd1e5a5e77bf49c7bc7ba1c55741634c |
|---|
| 출처 메모 | uspto-grants-1980_07 |
|---|
