Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-2-nitroanisole → 5-Chloro-2-methoxyaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-2-nitroanisole | HCID 66631 | — |
| 촉매 | Nickel | HCID 935 | — |
| 생성물 | 5-Chloro-2-methoxyaniline | HCID 66763 | — |
반응 단계
0.037 mol (7 g) of 4-chloro-2-nitroanisole is dissolved in 100 ml of absolute alcohol and 3 g of nickel prepared by the RANEY process are added. The solution is hydrogenated at atmospheric pressure and at room temperature while stirring. The catalyst is separated and then washed with two portions of 20 ml of boiling ethanol. The alcoholic solution is concentrated under reduced pressure; the 2-amino-4-chloroanisole crystallizes.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04211776 |
| 출처 데이터셋 | uspto-grants-1980_07 |
| ORD ID | ord-8d2027cedc054e0d925f8ce20ae21344 |
| 출처 메모 | uspto-grants-1980_07 |