Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → N-(5-Chloro-2-methoxyphenyl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | 5-Chloro-2-methoxyaniline | HCID 66763 | — |
| 촉매 | Zinc | HCID 23994 | — |
| 생성물 | N-(5-Chloro-2-methoxyphenyl)acetamide | HCID 346203 | — |
반응 단계
0.2 mol (31.5 g) of 2-amino-4-chloroanisole, 40 ml of absolute alcohol, 20 ml of acetic anhydride and a pinch of zinc powder are placed in a 150 ml flask; the solution is brought to reflux for 30 minutes. The reaction liquid is poured onto crushed ice. The product obtained is separated; it is crystallized in a methanol/water mixture (20/80).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04211776 |
| 출처 데이터셋 | uspto-grants-1980_07 |
| ORD ID | ord-c42d966b02af44adb9dfab5d9b71aeeb |
| 출처 메모 | uspto-grants-1980_07 |