Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(3-O-Acetyl-5-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)thymine → Fmau
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(3-O-Acetyl-5-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)thymine | HCID 54100196 | — |
| 용매 | Ammonia | HCID 222 | — |
| 생성물 | Fmau | HCID 72327 | 83.3% |
반응 단계
1-(3-O-Acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)thymine (150 mg) is dissolved in saturated methanolic ammonia (15 ml), and the mixture left standing for 16 hours. The solvent is removed by evaporation in vacuo, and the residue crystallized from water to give 80 mg of 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)thymine, m.p. 185°-185.5°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04211773 |
| 출처 데이터셋 | uspto-grants-1980_07 |
| ORD ID | ord-cff7bce3c6f54dc7b791314265853658 |
| 출처 메모 | uspto-grants-1980_07 |