Safrole → Safrole oxide

HRID 2057691

반응식

HRID 2057691 반응식
[CH2:1]([C:4]1[CH:12]=[CH:11][C:7]2[O:8][CH2:9][O:10][C:6]=2[CH:5]=1)[CH:2]=[CH2:3].CCC(OO)=[O:16]>C1C=CC=CC=1>[O:16]1[CH2:3][CH:2]1[CH2:1][C:4]1[CH:12]=[CH:11][C:7]2[O:8][CH2:9][O:10][C:6]=2[CH:5]=1

참가 물질

4

반응물 2

HCID 5144SafroleHCID 65136Perpropionic acid

생성물 1

HCID 101123Safrole oxide

시약·촉매·용매 1

HCID 241Benzene용매

반응 조건

온도
40 °C

실험 절차

19.90 g (0.11 mol) of 5-(2-propenyl)-1,3-benzodioxole were initially introduced into a double-walled flask having a stirrer and reflux condenser and are warmed to 40° C. 43.58 g (0.10 mol) of a 20.58% strength solution of perpropionic acid in benzene were added dropwise, whilst stirring, and stirring was continued at this temperature for a further 5 hours. Titrimetric analysis then showed a peracid conversion of 98%. Analysis of gas chromatography gave a selectivity for the 5-(oxiranylmethyl)-1,3-benzodioxole formed of 61%.

후처리

  1. temperaturereflux condenser
  2. stirringstirring

출처 및 근거

ORD 기록
ord-f1c6d27f486a454ab0f664927776b184
출처 데이터셋
uspto-grants-1980_07
특허 번호
US04212809

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