Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → Canthaxanthin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Sodium Iodide | HCID 5238 | — |
| 반응물 | Sodium Carbonate | HCID 10340 | — |
| 반응물 | Sodium Chlorate | HCID 516902 | — |
| 반응물 | β,β-Carotene-4,4'-diol | HCID 11757703 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | Canthaxanthin | HCID 5281227 | 94,872.398% |
반응 단계
An aqueous solution of 3.2 g of sodium chlorate and 20 mg of sodium iodide, dissolved in 20 ml of water, is added to 500 mg of racemic isozeaxanthin dissolved in 50 ml of chloroform, the two-phase mixture is stirred thoroughly at room temperature, and 5 ml of 0.01N sulfuric acid is added. After an hour, the mixture is neutralized with dilute sodium carbonate solution, the phases are separated, and the organic phase is washed with water and dried over sodium sulfate. The solvent is distilled off under reduced pressure, 50 ml of heptane is added to the residue, and the whole is refluxed for 1 hour. After cooling, filtration gives 471 g (94% of theory) of canthaxanthin.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04212827 |
| 출처 데이터셋 | uspto-grants-1980_07 |
| ORD ID | ord-d995584d61d8457c8560b1023dcc81b7 |
| 출처 메모 | uspto-grants-1980_07 |