Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylamine → 4-(Methylamino)-3-nitrophenyl phenyl ketone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylamine | HCID 6329 | — |
| 반응물 | Sulfolane | HCID 31347 | — |
| 반응물 | 4-Chloro-3-nitrobenzophenone | HCID 41743 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-(Methylamino)-3-nitrophenyl phenyl ketone | HCID 96689 | — |
반응 단계
11 g of 4-chloro-3-nitro-benzophenone, 20 g of methylamine, 153.4 g of methanol and 27.5 g of sulpholane are warmed to 125° for 15 hours in a closed vessel. The reaction solution is evaporated to dryness, the residue is boiled thoroughly with 400 ml of 2 N hydrochloric acid for 20 minutes and the precipitate is filtered off, washed with water and dissolved in methylene chloride. After drying over sodium sulphate and evaporating, 4-methylamino-3-nitro-benzophenone with a melting point of 198°-201° is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04213993 |
| 출처 데이터셋 | uspto-grants-1980_07 |
| ORD ID | ord-ace2d1fe7e91416598de2d7587d90002 |
| 출처 메모 | uspto-grants-1980_07 |