4-[15-(Trifluoromethyl)pentadecylamino]benzoic acid → HCID 22344169, 화합물

HRID 2058752노트

반응식

HRID 2058752 반응식
FC(F)(F)CCCCCCCCCCCCCCCN[C:19]1[CH:27]=[CH:26][C:22]([C:23](O)=[O:24])=[CH:21][CH:20]=1.C(COC)OC.C(Cl)[Cl:37]>>[ClH:37].[C:23]([Cl:37])(=[O:24])[C:22]1[CH:26]=[CH:27][CH:19]=[CH:20][CH:21]=1

참가 물질

3

반응물 2

HCID 128316104-[15-(Trifluoromethyl)pentadecylamino]benzoic acidHCID 86634710Dimethoxyethane methylene chloride

생성물 1

HCID 22344169HCID 22344169, 화합물

실험 절차

A cold solution of 25 g. of 4-[15-(trifluoromethyl)pentadecylamino]benzoic acid in 500 ml. dimethoxyethane-methylene chloride (4:1) is prepared and dry hydrochloric acid is bubbled through the solution until no more precipitate forms. The solution is treated with 25 ml. thionyl chloride and refluxed until all of the precipitate has dissolved. The solvents are evaporated to yield 4-[15-(trifluoromethyl)pentadecylamino)]benzoyl chloride hydrochloride as an orange, semi-crystalline mass.

후처리

  1. customdry hydrochloric acid is bubbled through the solution until no more precipitate forms
  2. additionThe solution is treated with 25 ml
  3. temperaturethionyl chloride and refluxed until all of the precipitate
  4. dissolutionhas dissolved
  5. customThe solvents are evaporated

출처 및 근거

ORD 기록
ord-81c3ba1b43a34151b255845c0c7870b7
출처 데이터셋
uspto-grants-1982_03
특허 번호
US04318914

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