HCID 59311794, 화합물 → 9-Phenyl-9-(pyrrolidin-1-yl)-3-azaspiro[5.5]undecane

HRID 2059908노트

반응식

HRID 2059908 반응식
C([N:4]1[CH2:9][CH2:8][C:7]2([CH2:14][CH2:13][C:12]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)([N:15]3[CH2:19][CH2:18][CH2:17][CH2:16]3)[CH2:11][CH2:10]2)[CH2:6][CH2:5]1)C=C.CN(C)C1(C2C=CC=CC=2)CCC2(CCNCC2)CC1>>[C:20]1([C:12]2([N:15]3[CH2:16][CH2:17][CH2:18][CH2:19]3)[CH2:11][CH2:10][C:7]3([CH2:6][CH2:5][NH:4][CH2:9][CH2:8]3)[CH2:14][CH2:13]2)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

참가 물질

3

반응물 2

HCID 59311794HCID 59311794, 화합물HCID 673149673-Allyl-9-phenyl-9-(pyrrolidin-1-yl)-3-azaspiro[5.5]undecane

생성물 1

HCID 593117849-Phenyl-9-(pyrrolidin-1-yl)-3-azaspiro[5.5]undecane수율 90%

실험 절차

The reaction was performed starting from 3-allyl-9-phenyl-9-(pyrrolidin-1-yl)-3-azaspiro[5.5]undecane in an analogous manner to stage 9 amine (A1). Yield: 90%

출처 및 근거

ORD 기록
ord-a026411975bd4f3c9e24ead3066e779b
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08278319B2

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