HCID 59311794, 화합물 → 9-(3-fluorophenyl)-N,N-dimethyl-3-azaspiro[5.5]undecan-9-amine

HRID 2059911노트

반응식

HRID 2059911 반응식
C([N:4]1[CH2:9][CH2:8][C:7]2([CH2:14][CH2:13][C:12]([C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([F:24])[CH:19]=3)([N:15]([CH3:17])[CH3:16])[CH2:11][CH2:10]2)[CH2:6][CH2:5]1)C=C.CN(C)C1(C2C=CC=CC=2)CCC2(CCNCC2)CC1>>[F:24][C:20]1[CH:19]=[C:18]([C:12]2([N:15]([CH3:17])[CH3:16])[CH2:11][CH2:10][C:7]3([CH2:8][CH2:9][NH:4][CH2:5][CH2:6]3)[CH2:14][CH2:13]2)[CH:23]=[CH:22][CH:21]=1

참가 물질

3

반응물 2

HCID 59311794HCID 59311794, 화합물HCID 673154603-allyl-9-(3-fluorophenyl)-N,N-dimethyl-3-azaspiro[5.5]undecan-9-amine

생성물 1

HCID 593118149-(3-fluorophenyl)-N,N-dimethyl-3-azaspiro[5.5]undecan-9-amine

실험 절차

The reaction was performed starting from 3-allyl-9-(3-fluorophenyl)-N,N-dimethyl-3-azaspiro[5.5]undecan-9-amine in an analogous manner to stage 9 amine (A1). Yield: quantitative

출처 및 근거

ORD 기록
ord-54b4d0fed971423784c92d0ec79ab1b9
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08278319B2

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