Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridinium chloride → HCID 42613602, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridinium chloride | HCID 10176127 | — |
| 반응물 | 1-[6'-(5-Fluoro-2,3-dihydro-indole-1-carbonyl)-2'-methoxy-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-4-yl]-1,3-dihydro-imidazo[4,5-b]pyridin-2-one | HCID 58386552 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 42613602 | HCID 42613602 | — |
반응 단계
A well stirred mixture of 40 mg (0.082 mmol) 1-[6′-(5-fluoro-2,3-dihydro-indole-1-carbonyl)-2′-methoxy-3,4,5,6-tetrahydro-2H-[1,4′]bipyridinyl-4-yl]-1,3-dihydro-imidazo-[4,5-b]pyridin-2-one and 0.020 g (1.7 mmol) pyridine hydrochloride was kept in a melt for 2 min using a hot air blower. After the reaction had cooled the mixture was dissolved in DMF and purified by preparative HPLC. The product-containing fractions were combined and lyophilised.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08278336B2 |
| 출처 데이터셋 | uspto-grants-2012_10 |
| ORD ID | ord-397ecc7a60864ca6a726ef71959024f5 |
| 출처 메모 | uspto-grants-2012_10 |