2-Ethoxybenzoyl chloride → 1-(2-Ethoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester

HRID 2060235노트

반응식

HRID 2060235 반응식
[CH2:1]([O:3][C:4]([CH:6]1[CH2:10][CH2:9][NH:8][CH2:7]1)=[O:5])[CH3:2].[CH2:11]([O:13][C:14]1[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=1[C:16](Cl)=[O:17])[CH3:12]>>[CH2:1]([O:3][C:4]([CH:6]1[CH2:10][CH2:9][N:8]([C:16](=[O:17])[C:15]2[CH:19]=[CH:20][CH:21]=[CH:22][C:14]=2[O:13][CH2:11][CH3:12])[CH2:7]1)=[O:5])[CH3:2]

참가 물질

3

반응물 2

HCID 30163972-Ethoxybenzoyl chlorideHCID 12896002Ethyl pyrrolidine-3-carboxylate

생성물 1

HCID 593221811-(2-Ethoxy-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester수율 83%

실험 절차

The title compound was prepared according to the method described for Preparation 2 using pyrrolidine-3-carboxylic acid ethyl ester (see Preparation 1) and 2-ethoxy-benzoyl chloride to afford the title compound as a pale yellow oil (5.13 g, 83%).

후처리

  1. customThe title compound was prepared

출처 및 근거

ORD 기록
ord-5e77c7e39a32448e9f3d159b16158cc4
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08278343B2

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