Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 2371-31-5
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | Glycine, N-(4-chlorophenyl)-, ethyl ester | HCID 302644 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2371-31-5 | HCID 302647 | 59% |
반응 단계
Ethyl 2-(4-chlorophenylamino)acetate (A) (25.6 g, 120 mmol) and hydrazine monohydrate (7.0 mL, 144 mmol) were heated to reflux in ethanol (120 mL) for 22 hours. After concentration in vacuo, the solid obtained was recrystallised from ethanol to yield the title compound (14.0 g, 59%) as a pale brown powder. 1H NMR (400 MHz, CDCl3) δ 3.85 (2H, d), 4.18 (2H, br), 6.53 (2H, d), 7.16 (2H, d), 7.60 (1H, br).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08283351B2 |
| 출처 데이터셋 | uspto-grants-2012_10 |
| ORD ID | ord-4de39e719876495c897ec661c521281c |
| 출처 메모 | uspto-grants-2012_10 |