HCID 58154431, 화합물 → HCID 59205151, 화합물

반응식

Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=2)[N:3]=1.[NH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([N:28]([CH3:30])[CH3:29])[C:23]=1[S:31]([NH2:34])(=[O:33])=[O:32]>>[CH3:29][N:28]([CH3:30])[C:24]1[CH:25]=[CH:26][CH:27]=[C:22]([NH:21][C:2]2[CH:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]3[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=3)[N:3]=2)[C:23]=1[S:31]([NH2:34])(=[O:33])=[O:32]

참가 물질

반응물 2

HCID 58154431HCID 58154431, 화합물

HCID 66915943HCID 66915943, 화합물

생성물 1

HCID 59205151HCID 59205151, 화합물

실험 절차

2-(Dimethyl-amino)-6-[2-(3,4,5-trimethoxy-phenylamino)-pyrimidin-4-ylamino]-benzenesulfonamide is prepared as described in Example 1 step C by using 4-chloro-pyrimidin-2-yl)-(3,4,5-trimethoxy-phenyl)-amine (example 1 step A) and 2-amino-6-dimethylamino-benzenesulfonamide.

출처 및 근거

ORD 기록: ord-f226462a5f394895a457796a0662d0c2
출처 데이터셋: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08283356B2

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