Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonium Acetate → 4-amino-8-(cyclopentyloxy)-7-methoxy-2H-chromen-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonium Acetate | HCID 517165 | — |
| 반응물 | 8-(cyclopentyloxy)-4-hydroxy-7-methoxy-2H-chromen-2-one | HCID 77174792 | — |
| 용매 | M-Xylene | HCID 7929 | — |
| 생성물 | 4-amino-8-(cyclopentyloxy)-7-methoxy-2H-chromen-2-one | HCID 77174793 | — |
반응 단계
A mixture of 8-(cyclopentyloxy)-4-hydroxy-7-methoxy-2H-chromen-2-one (450 mg, 1.63 mmol, Example 1, Step 2), ammonium acetate (3.0 g, 39 mmol), and anhydrous m-xylene (8 mL) was refluxed under N2. After 3 h, the reaction was concentrated and purified by silica gel chromatography (3:2→0:1; hexanes:ethyl acetate) to give 4-amino-8-(cyclopentyloxy)-7-methoxy-2H-chromen-2-one: MS (ESI): 275.9.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745646B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-04761b64a3d74a64b013bacdf263a064 |
| 출처 메모 | uspto-grants-2010_06 |