HCID 60911320, 화합물 → HCID 59324072, 화합물

반응식

Br[C:2]1[CH:3]=[CH:4][C:5]([N:10]2[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]2)=[C:6]([CH:9]=1)[C:7]#[N:8].[CH:16]1([CH2:19][N:20]2[CH:24]=[N:23][C:22]([NH2:25])=[N:21]2)[CH2:18][CH2:17]1>>[CH:16]1([CH2:19][N:20]2[CH:24]=[N:23][C:22]([NH:25][C:2]3[CH:3]=[CH:4][C:5]([N:10]4[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]4)=[C:6]([CH:9]=3)[C:7]#[N:8])=[N:21]2)[CH2:18][CH2:17]1

참가 물질

반응물 2

HCID 60911320HCID 60911320, 화합물

HCID 669615175-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile

생성물 1

HCID 59324072HCID 59324072, 화합물

실험 절차

Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 1-cyclopropylmethyl-1H-[1,2,4]triazol-3-ylamine. The title compound was obtained as a yellowish foam (Yield=45%). MS ISP (m/e): 320.1 (100) [(M+H)+].

후처리

customPrepared in analogy to example 1b)

출처 및 근거

ORD 기록: ord-792ba142ac0a4ac88c6461738885b47a
출처 데이터셋: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08288403B2

반응 노트

불러오는 중…