1-benzyl-1H-pyrazol-4-amine → 5-(1-Benzyl-1H-pyrazol-4-ylamino)-2-(4-methyl-imidazol-1-yl)-benzonitrile
반응식
Br[C:2]1[CH:3]=[CH:4][C:5]([N:10]2[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]2)=[C:6]([CH:9]=1)[C:7]#[N:8].[CH2:16]([N:23]1[CH:27]=[C:26]([NH2:28])[CH:25]=[N:24]1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([N:23]1[CH:27]=[C:26]([NH:28][C:2]2[CH:3]=[CH:4][C:5]([N:10]3[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]3)=[C:6]([CH:9]=2)[C:7]#[N:8])[CH:25]=[N:24]1)[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1참가 물질
3
실험 절차
Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 1-benzyl-1H-pyrazol-4-ylamine. The title compound was obtained as a yellow oil (Yield=40%). MS ISP (m/e): 355.2 (100) [(M+H)+].
후처리
- customPrepared in analogy to example 1b)
출처 및 근거
- ORD 기록
- ord-71a524a2503a43d5a4903da60fd7e388
- 출처 데이터셋