Water → Tert-butyl{1-[4-(2-phenyl-9-pyrazin-2-yl[1,2,4]triazolo[4',3':1,6]pyrido[2,3-b]pyrazin-3-yl)phenyl]cyclobutyl}carbamate

반응식

Cl[C:2]1[N:3]=[C:4]2[CH:17]=[CH:16][C:15]3=[N:18][N:19]=[C:20]([C:21]4[CH:26]=[N:25][CH:24]=[CH:23][N:22]=4)[N:14]3[C:5]2=[N:6][C:7]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.CC1(C)C(C)(C)OB([C:35]2[CH:40]=[CH:39][C:38]([C:41]3([NH:45][C:46](=[O:52])[O:47][C:48]([CH3:51])([CH3:50])[CH3:49])[CH2:44][CH2:43][CH2:42]3)=[CH:37][CH:36]=2)O1.C(=O)([O-])[O-].[K+].[K+].O>CN1C(=O)CCC1.CO.CC(C)([P](C(C)(C)C)([Pd][P](C(C)(C)C)(C(C)(C)C)C(C)(C)C)C(C)(C)C)C.O1CCOCC1.CN1C(=O)CCC1>[C:8]1([C:7]2[N:6]=[C:5]3[N:14]4[C:20]([C:21]5[CH:26]=[N:25][CH:24]=[CH:23][N:22]=5)=[N:19][N:18]=[C:15]4[CH:16]=[CH:17][C:4]3=[N:3][C:2]=2[C:35]2[CH:36]=[CH:37][C:38]([C:41]3([NH:45][C:46](=[O:52])[O:47][C:48]([CH3:49])([CH3:50])[CH3:51])[CH2:44][CH2:43][CH2:42]3)=[CH:39][CH:40]=2)[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1