Thioacetamide → 5-(3-Fluoro-phenyl)-2-methyl-thiazole-4-carboxylic acid methyl ester

HRID 2064460노트

반응식

HRID 2064460 반응식
[CH3:1][O:2][C:3](=[O:15])[C:4](=O)[CH:5](Cl)[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([F:12])[CH:7]=1.[C:16]([NH2:19])(=[S:18])[CH3:17]>>[CH3:1][O:2][C:3]([C:4]1[N:19]=[C:16]([CH3:17])[S:18][C:5]=1[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([F:12])[CH:7]=1)=[O:15]

참가 물질

3

반응물 2

HCID 2723949ThioacetamideHCID 57437155Methyl 3-chloro-3-(3-fluorophenyl)-2-oxopropanoate

생성물 1

HCID 574371645-(3-Fluoro-phenyl)-2-methyl-thiazole-4-carboxylic acid methyl ester

실험 절차

prepared by reaction of 3-chloro-3-(3-fluoro-phenyl)-2-oxo-propionic acid methyl ester with thioacetamide. LC-MS: tR=0.91 min; [M+H]+=252.1.

출처 및 근거

ORD 기록
ord-2432f20954a045e49b9d1e5a7746fdc3
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08288429B2

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