4-Aminobenzoic Acid → HCID 59320718, 화합물

HRID 2064555노트

반응식

HRID 2064555 반응식
[CH3:1][CH:2]1[CH2:7][CH2:6][C:5](=O)[CH:4]([CH2:9][C:10]([C:12]2[N:16]([CH3:17])[C:15]3[CH:18]=[CH:19][CH:20]=[CH:21][C:14]=3[N:13]=2)=O)[CH2:3]1.[NH2:22][C:23]1[CH:31]=[CH:30][C:26]([C:27]([OH:29])=[O:28])=[CH:25][CH:24]=1>>[CH3:1][CH:2]1[CH2:7][CH2:6][C:5]2[N:22]([C:23]3[CH:31]=[CH:30][C:26]([C:27]([OH:29])=[O:28])=[CH:25][CH:24]=3)[C:10]([C:12]3[N:16]([CH3:17])[C:15]4[CH:18]=[CH:19][CH:20]=[CH:21][C:14]=4[N:13]=3)=[CH:9][C:4]=2[CH2:3]1

참가 물질

3

반응물 2

HCID 9784-Aminobenzoic AcidHCID 68596241HCID 68596241, 화합물

생성물 1

HCID 59320718HCID 59320718, 화합물수율 60%

실험 절차

Following the general methods as outlined under Intermediate 13, starting from 4-methyl-2-[2-(1-methyl-1H-benzimidazol-2-yl)-2-oxoethyl]cyclohexanone and 4-aminobenzoic acid, the title compound was isolated in 60% yield (98% purity by HPLC). MS(ESI+): 386.6; MS(ESI−): 384.2.

출처 및 근거

ORD 기록
ord-2ad90dfc5d754d3d94c6ac6726d7e69a
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08288432B2

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