참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1H-Indazol-3-ylmethanol | HCID 178520026 | — |
| 촉매 | HCID 178418406 | HCID 178418406 | — |
| 용매 | 1,2-Dimethoxyethane | HCID 8071 | — |
| 생성물 | HCID 178520025 | HCID 178520025 | 90.2% |
반응 단계
A solution of 2.27 g of (1H-indazol-3-yl)methanol in 220 ml of 1,2-dimethoxyethane is added to 13.32 g of manganese dioxide. After one hour at a temperature in the region of 20° C., the reaction mixture is refluxed for 15 minutes. After cooling to a temperature in the region of 20° C., the reaction medium is filtered through a sinter funnel packed with Celite. The collected filtrate is concentrated under reduced pressure at a temperature in the region of 40° C. 2.02 g of 1H-indazole-3-carboxaldehyde are thus obtained in the form of a yellow powder, the characteristics of which are as follows:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08288425B2 |
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| 출처 데이터셋 | uspto-grants-2012_10 |
|---|
| ORD ID | ord-92e718e1225b4f5b84e6107ab8c77e91 |
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| 출처 메모 | uspto-grants-2012_10 |
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