Cyclopropanecarbothioamide → 2-Cyclopropyl-5-(3-fluoro-phenyl)-thiazole-4-carboxylic Acid Methyl Ester
반응식
[CH3:1][O:2][C:3](=[O:15])[C:4](=O)[CH:5](Cl)[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([F:12])[CH:7]=1.[CH:16]1([C:19](=[S:21])[NH2:20])[CH2:18][CH2:17]1>>[CH3:1][O:2][C:3]([C:4]1[N:20]=[C:19]([CH:16]2[CH2:18][CH2:17]2)[S:21][C:5]=1[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([F:12])[CH:7]=1)=[O:15]참가 물질
3
실험 절차
prepared by reaction of 3-chloro-3-(3-fluoro-phenyl)-2-oxo-propionic acid methyl ester with cyclopropanecarbothioic acid amide. LC-MS: tR=1.02 min; [M+H]+=278.0.
출처 및 근거
- ORD 기록
- ord-a639260e5ec446c0b8bf9f23dc275a7e
- 출처 데이터셋
- uspto-grants-2012_10
- 특허 번호
- US08288435B2
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