3-Methylimidazo(2,1-b)(1,3)thiazole-5-carboxylic acid → HCID 86653657, 화합물

HRID 2064867

반응식

HRID 2064867 반응식
[NH2:1][C:2]1[S:3][C:4]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([F:23])[CH:18]=2)=[C:5]([C:7]([N:9]2[C@H:14]([CH2:15][NH2:16])[CH2:13][C@H:12]3[C@@H:10]2[CH2:11]3)=[O:8])[N:6]=1.[CH3:24][C:25]1[N:26]2[C:32]([C:33](O)=[O:34])=[CH:31][N:30]=[C:27]2[S:28][CH:29]=1>>[NH2:1][C:2]1[S:3][C:4]([C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([F:23])[CH:18]=2)=[C:5]([C:7]([N:9]2[C@H:14]([CH2:15][NH:16][C:33]([C:32]3[N:26]4[C:27]([S:28][CH:29]=[C:25]4[CH3:24])=[N:30][CH:31]=3)=[O:34])[CH2:13][C@H:12]3[C@@H:10]2[CH2:11]3)=[O:8])[N:6]=1

참가 물질

3

반응물 2

HCID 212564713-Methylimidazo(2,1-b)(1,3)thiazole-5-carboxylic acidHCID 86653658[2-amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl)-methanone

생성물 1

HCID 86653657HCID 86653657, 화합물

실험 절차

prepared by reaction of [2-amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hex-2-yl)-methanone with 3-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid. LC-MS (basic): tR=0.76 min; [M+H]+=497.1.

출처 및 근거

ORD 기록
ord-61a51e14501843c08790c52763b8dc9c
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08288435B2

연결된 노트

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