2-Chloro-3,6-difluorocinnamic acid → HCID 66929336, 화합물

반응식

[CH3:1][C:2]1([CH2:7][CH2:8][CH2:9][CH2:10][N:11]2[CH:15]=[CH:14][C:13]([NH2:16])=[N:12]2)[O:6]CCO1.[Cl:17][C:18]1[C:23]([F:24])=[CH:22][CH:21]=[C:20]([F:25])[C:19]=1/[CH:26]=[CH:27]/[C:28](O)=[O:29]>>[Cl:17][C:18]1[C:23]([F:24])=[CH:22][CH:21]=[C:20]([F:25])[C:19]=1/[CH:26]=[CH:27]/[C:28]([NH:16][C:13]1[CH:14]=[CH:15][N:11]([CH2:10][CH2:9][CH2:8][CH2:7][C:2](=[O:6])[CH3:1])[N:12]=1)=[O:29]

참가 물질

반응물 2

HCID 57083902-Chloro-3,6-difluorocinnamic acid

HCID 669284811-[4-(2-Methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-3-ylamine

생성물 1

HCID 66929336HCID 66929336, 화합물

실험 절차

Following general procedure B followed by either C or D, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-3-ylamine and (E)-3-(2-chloro-3,6-difluoro-phenyl)-acrylic acid.

출처 및 근거

ORD 기록: ord-3f72fe487a1c4fd68e577ef3ec296722
출처 데이터셋: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08288419B2

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