Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
trans-2-Chloro-6-fluorocinnamic acid → (E)-3-(2-Chloro-6-fluoro-phenyl)-N-{1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-yl}-acrylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | trans-2-Chloro-6-fluorocinnamic acid | HCID 5324668 | — |
| 반응물 | 1-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine | HCID 66929369 | — |
| 생성물 | (E)-3-(2-Chloro-6-fluoro-phenyl)-N-{1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-yl}-acrylamide | HCID 66928400 | — |
반응 단계
Following general procedure B, starting from 1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine and (E)-3-(2-chloro-6-fluoro-phenyl)-acrylic acid. LC-MS-conditions 05b: tR=1.14 min; [M+H]+=410.0.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08288419B2 |
| 출처 데이터셋 | uspto-grants-2012_10 |
| ORD ID | ord-8875b07adfb443649ad0e15c3b5b5dd3 |
| 출처 메모 | uspto-grants-2012_10 |