3-Methylcinnamic acid → HCID 66929121, 화합물

반응식

[F:1][C:2]([C:5]1[O:9][C:8]([CH2:10][N:11]2[CH:15]=[CH:14][C:13]([NH2:16])=[N:12]2)=[CH:7][CH:6]=1)([F:4])[CH3:3].[C:17]1([CH3:28])[CH:22]=[CH:21][CH:20]=[C:19](/[CH:23]=[CH:24]/[C:25](O)=[O:26])[CH:18]=1>>[F:4][C:2]([C:5]1[O:9][C:8]([CH2:10][N:11]2[CH:15]=[CH:14][C:13]([NH:16][C:25](=[O:26])/[CH:24]=[CH:23]/[C:19]3[CH:18]=[C:17]([CH3:28])[CH:22]=[CH:21][CH:20]=3)=[N:12]2)=[CH:7][CH:6]=1)([F:1])[CH3:3]

참가 물질

반응물 2

HCID 20634483-Methylcinnamic acid

HCID 669293691-[5-(1,1-Difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine

생성물 1

HCID 66929121HCID 66929121, 화합물

실험 절차

Following general procedure B, starting from 1-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine and (E)-3-m-tolyl-acrylic acid. LC-MS-conditions 05b: tR=1.13 min; [M+H]+=372.16.

출처 및 근거

ORD 기록: ord-6163c35f6b934683824c43571522b266
출처 데이터셋: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08288419B2

반응 노트

불러오는 중…