Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(E)-3-(2,5-difluoro-4-methoxy-phenyl)-acrylic acid → (E)-N-[1-(5-Acetyl-furan-2-ylmethyl)-1H-pyrazol-4-yl]-3-(2,5-difluoro-4-methoxy-phenyl)-acrylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (E)-3-(2,5-difluoro-4-methoxy-phenyl)-acrylic acid | HCID 5928340 | — |
| 반응물 | 1-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine | HCID 66928611 | — |
| 생성물 | (E)-N-[1-(5-Acetyl-furan-2-ylmethyl)-1H-pyrazol-4-yl]-3-(2,5-difluoro-4-methoxy-phenyl)-acrylamide | HCID 66929048 | — |
반응 단계
Following general procedure B followed by T, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-4-ylamine and (E)-3-(2,5-difluoro-4-methoxy-phenyl)-acrylic acid. LC-MS-conditions 01b: tR=0.86 min; [M+H]+=402.17.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08288419B2 |
| 출처 데이터셋 | uspto-grants-2012_10 |
| ORD ID | ord-743d55fd9aa04e5f94692c82327cccb8 |
| 출처 메모 | uspto-grants-2012_10 |