5-Phenyl-1,3-oxazole-4-carboxylic acid → 5-Phenyl-oxazole-4-carboxylic acid [1-(4-acetyl-thiazol-2-ylmethyl)-1H-pyrazol-3-yl]-amide

HRID 2065358

반응식

HRID 2065358 반응식
[CH3:1][C:2]1([C:7]2[N:8]=[C:9]([CH2:12][N:13]3[CH:17]=[CH:16][C:15]([NH2:18])=[N:14]3)[S:10][CH:11]=2)[O:6]CCO1.[C:19]1([C:25]2[O:29][CH:28]=[N:27][C:26]=2[C:30](O)=[O:31])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[C:2]([C:7]1[N:8]=[C:9]([CH2:12][N:13]2[CH:17]=[CH:16][C:15]([NH:18][C:30]([C:26]3[N:27]=[CH:28][O:29][C:25]=3[C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)=[O:31])=[N:14]2)[S:10][CH:11]=1)(=[O:6])[CH3:1]

참가 물질

3

반응물 2

HCID 27762995-Phenyl-1,3-oxazole-4-carboxylic acidHCID 669289951-[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine

생성물 1

HCID 669282735-Phenyl-oxazole-4-carboxylic acid [1-(4-acetyl-thiazol-2-ylmethyl)-1H-pyrazol-3-yl]-amide

실험 절차

Following general procedure B followed by C, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-thiazol-2-ylmethyl]-1H-pyrazol-3-ylamine and 5-phenyl-oxazole-4-carboxylic acid. LC-MS-conditions 01: tR=0.92 min; [M+H]+=393.99.

출처 및 근거

ORD 기록
ord-647c31b25f70424aae37c3ccec9de11b
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08288419B2

연결된 노트

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