3-fluoro-DL-tyrosine → HCID 45255159, 화합물

HRID 2065635노트

반응식

HRID 2065635 반응식
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[F:16][C:17]1[CH:18]=[C:19]([CH:26]=[CH:27][C:28]=1[OH:29])[CH2:20][CH:21]([C:23]([OH:25])=[O:24])[NH2:22]>>[C:23]([CH:21]([NH:22][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)[CH2:20][C:19]1[CH:26]=[CH:27][C:28]([OH:29])=[C:17]([F:16])[CH:18]=1)([OH:25])=[O:24]

참가 물질

3

반응물 2

HCID 921003-fluoro-DL-tyrosineHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

생성물 1

HCID 45255159HCID 45255159, 화합물

실험 절차

In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 3-fluoro-4-hydroxy-DL-phenylalanine to provide the title compound in good yield.

출처 및 근거

ORD 기록
ord-2436f02bbceb4f19a6fd9e93e3c4aeca
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08288549B2

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