Ethyl 2-amino-3-(pyridin-2-yl)propanoate → HCID 67357623, 화합물

HRID 2065707노트

반응식

HRID 2065707 반응식
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[CH2:16]([O:18][C:19](=[O:29])[CH:20]([NH2:28])[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=1)[CH3:17]>>[Cl:15][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([NH:28][CH:20]([C:19]([O:18][CH2:16][CH3:17])=[O:29])[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=1)[C:11]([C:12]([OH:14])=[O:13])=[CH:10]2

참가 물질

3

반응물 2

HCID 4436717Ethyl 2-amino-3-(pyridin-2-yl)propanoateHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

생성물 1

HCID 67357623HCID 67357623, 화합물

실험 절차

In close analogy to the procedure described in Example 43, 2,6-dichloro-quinoline-3-carboxylic acid is reacted with 2-amino-3-pyridin-2-yl-propionic acid ethyl ester to provide after chromatographical separation the title compound in moderate yield.

후처리

  1. customto provide
  2. customafter chromatographical separation the title compound in moderate yield

출처 및 근거

ORD 기록
ord-a2f4365e567e4613908f715266faf8bb
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08288549B2

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