Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Nitrobenzyl bromide → 4-(3,5-Dichloropyridin-4-ylamino)-7-methoxy-8-(4-nitrobenzyloxy)-2H-chromen-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Nitrobenzyl bromide | HCID 66011 | — |
| 반응물 | 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one | HCID 24849570 | — |
| 생성물 | 4-(3,5-Dichloropyridin-4-ylamino)-7-methoxy-8-(4-nitrobenzyloxy)-2H-chromen-2-one | HCID 24849621 | — |
반응 단계
The title compound was prepared from 1-(bromomethyl)-4-nitrobenzene and 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one (Example 29) following the procedure outlined in Example 25. 1H NMR (400 MHz, DMSO-d6): δ 9.55 (s, 1H), 8.81 (s, 2H), 8.25 (d, 2H), 7.99 (d, 1H), 7.80 (d, 2H), 7.25 (d, 1H), 5.20 (s, 2H), 4.66 (s, 1H), 3.93 (s, 3H); MS (ESI): 487.8.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745646B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-7da20564ac7f4eb4b9839fae9834f8f1 |
| 출처 메모 | uspto-grants-2010_06 |