(2-Chloro-4-o-tolylamino-phenyl)-(2-methyl-5-nitro-phenyl)-methanone → (5-Amino-2-methyl-phenyl)-(2-chloro-4-o-tolylamino-phenyl)-methanone

HRID 2067211노트

반응식

HRID 2067211 반응식
NC1C=CC(C)=C(C(C2C=CC(NC3C=CC(C(F)(F)F)=CC=3)=CC=2Cl)=O)C=1.[Cl:29][C:30]1[CH:35]=[C:34]([NH:36][C:37]2[CH:42]=[CH:41][CH:40]=[CH:39][C:38]=2[CH3:43])[CH:33]=[CH:32][C:31]=1[C:44]([C:46]1[CH:51]=[C:50]([N+:52]([O-])=O)[CH:49]=[CH:48][C:47]=1[CH3:55])=[O:45]>>[NH2:52][C:50]1[CH:49]=[CH:48][C:47]([CH3:55])=[C:46]([C:44]([C:31]2[CH:32]=[CH:33][C:34]([NH:36][C:37]3[CH:42]=[CH:41][CH:40]=[CH:39][C:38]=3[CH3:43])=[CH:35][C:30]=2[Cl:29])=[O:45])[CH:51]=1

참가 물질

3

반응물 2

HCID 68418373(2-Chloro-4-o-tolylamino-phenyl)-(2-methyl-5-nitro-phenyl)-methanoneHCID 68419668(5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-trifluoromethyl-phenylamino)-phenyl]-methanone

생성물 1

HCID 68417734(5-Amino-2-methyl-phenyl)-(2-chloro-4-o-tolylamino-phenyl)-methanone

실험 절차

The reaction was carried out similarly as described in the preparation of compound 415, using compound 417 (0.39 mmol). The crude product was used without any further purification.

후처리

  1. customThe crude product was used without any further purification

출처 및 근거

ORD 기록
ord-cfe0f526b9254355a236ce3800219f53
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08293772B2

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