(5-Amino-2-methyl-phenyl)-[2-chloro-4-(2-chloro-4-fluoro-phenylamino)-phenyl]-methanone → (5-Azido-2-methyl-phenyl)-[2-chloro-4-(2-chloro-4-fluoro-phenylamino)-phenyl]-methanone
반응식
[N:1](C1C=CC(C)=C(C(C2C=CC(NC3C=CC(C(F)(F)F)=CC=3)=CC=2Cl)=O)C=1)=[N+:2]=[N-].[NH2:31][C:32]1[CH:33]=[CH:34][C:35]([CH3:56])=[C:36]([C:38]([C:40]2[CH:45]=[CH:44][C:43]([NH:46][C:47]3[CH:52]=[CH:51][C:50]([F:53])=[CH:49][C:48]=3[Cl:54])=[CH:42][C:41]=2[Cl:55])=[O:39])[CH:37]=1>>[N:31]([C:32]1[CH:33]=[CH:34][C:35]([CH3:56])=[C:36]([C:38]([C:40]2[CH:45]=[CH:44][C:43]([NH:46][C:47]3[CH:52]=[CH:51][C:50]([F:53])=[CH:49][C:48]=3[Cl:54])=[CH:42][C:41]=2[Cl:55])=[O:39])[CH:37]=1)=[N+:1]=[N-:2]참가 물질
3
반응물 2
생성물 1
실험 절차
The reaction was carried out similarly as described in the preparation of compound 416, using compound 421 (0.21 mmol). The crude product was used without any further purification.
후처리
- customThe crude product was used without any further purification