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(5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-chloro-2-methyl-phenylamino)-phenyl]-methanone → (5-Azido-2-methyl-phenyl)-[2-chloro-4-(4-chloro-2-methyl-phenylamino)-phenyl]-methanone

HRID 2067259
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인쇄 미리보기

반응식

HRID 2067259 반응식
[N:1]([C:4]1[CH:5]=[CH:6][C:7]([CH3:30])=[C:8]([C:10]([C:12]2[CH:17]=[CH:16][C:15]([NH:18][C:19]3[CH:24]=[CH:23][C:22]([C:25](F)(F)F)=[CH:21][CH:20]=3)=[CH:14][C:13]=2[Cl:29])=[O:11])[CH:9]=1)=[N+:2]=[N-:3].NC1C=CC(C)=C(C(C2C=CC(NC3C=CC([Cl:53])=CC=3C)=CC=2Cl)=O)C=1>>[N:1]([C:4]1[CH:5]=[CH:6][C:7]([CH3:30])=[C:8]([C:10]([C:12]2[CH:17]=[CH:16][C:15]([NH:18][C:19]3[CH:20]=[CH:21][C:22]([Cl:53])=[CH:25][C:24]=3[CH3:23])=[CH:14][C:13]=2[Cl:29])=[O:11])[CH:9]=1)=[N+:2]=[N-:3]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

3

반응물 2

HCID 68419223(5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-chloro-2-methyl-phenylamino)-phenyl]-methanoneHCID 86605524(5-Azido-2-methyl-phenyl)-[2-chloro-4-(4-trifluoromethyl-phenylamino)-phenyl]-methanone

생성물 1

HCID 86605533(5-Azido-2-methyl-phenyl)-[2-chloro-4-(4-chloro-2-methyl-phenylamino)-phenyl]-methanone

실험 절차

The reaction was carried out similarly as described in the preparation of compound 416, using compound 444 (0.09 mmol). The crude product was used without any further purification.

후처리

  1. customThe crude product was used without any further purification

출처 및 근거

ORD 기록
ord-1daa10f1f334492bbde7b4c129561799
출처 데이터셋
uspto-grants-2012_10
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US08293772B2

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