참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | Methyl N-(4-methylpyridin-3-yl)carbamate | HCID 11672725 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1-Benzyl-3-methoxycarbonylamino-4-methyl-pyridinium bromide | HCID 66770203 | 101.8% |
반응 단계
1-(Bromomethyl)benzene (19 g, 111 mmol, 1.10 equiv.) was added to a solution of methyl 4-methylpyridin-3-ylcarbamate (17 g, 102 mmol, 1.00 equiv.) in toluene (500 mL). The solution was stirred at about 110° C. for about 16 hours. After cooling to ambient temperature, the solids were collected by filtration and washed with toluene to afford the title product as a light brown solid (35 g; yield=97%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08299084B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_10 |
|---|
| ORD ID | ord-ed2443c1174f4ec99825d61dc5ecf2ca |
|---|
| 출처 메모 | uspto-grants-2012_10 |
|---|
