Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
DL-2-Amino-1-hexanol → N-[6-(1-Hydroxymethyl-pentylamino)-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl]-methanesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | DL-2-Amino-1-hexanol | HCID 249006 | — |
| 반응물 | N-(6-fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide | HCID 58964482 | — |
| 생성물 | N-[6-(1-Hydroxymethyl-pentylamino)-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl]-methanesulfonamide | HCID 69338669 | 61% |
반응 단계
N-(6-Fluoro-7-nitro-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-methanesulfonamide (30 mg, 0.0943 mmol) is reacted with 2-amino-hexan-1-ol according to the GPA affording 24 mg (61%) of a purple powder. Rt=4.5 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08299085B2 |
| 출처 데이터셋 | uspto-grants-2012_10 |
| ORD ID | ord-e697243bebe7454a91642ccd98f06175 |
| 출처 메모 | uspto-grants-2012_10 |