Urea, 1-(m-boronophenyl)- → 5-Formyl-6-methoxy-3'-ureido-biphenyl-3-sulfonamide

반응식

Br[C:2]1[CH:3]=[C:4]([S:12]([NH2:15])(=[O:14])=[O:13])[CH:5]=[C:6]([CH:10]=[O:11])[C:7]=1[O:8][CH3:9].[NH:16]([C:20]1[CH:21]=[C:22](B(O)O)[CH:23]=[CH:24][CH:25]=1)[C:17]([NH2:19])=[O:18]>>[CH:10]([C:6]1[CH:5]=[C:4]([S:12]([NH2:15])(=[O:14])=[O:13])[CH:3]=[C:2]([C:24]2[CH:23]=[CH:22][CH:21]=[C:20]([NH:16][C:17]([NH2:19])=[O:18])[CH:25]=2)[C:7]=1[O:8][CH3:9])=[O:11]

참가 물질

반응물 2

HCID 3021600Urea, 1-(m-boronophenyl)-

HCID 866076983-Bromo-5-formyl-4-methoxy-benzenesulfonamide

생성물 1

HCID 866077135-Formyl-6-methoxy-3'-ureido-biphenyl-3-sulfonamide

실험 절차

Proceeding as in Reference 19, but substituting 3-bromo-5-formyl-4-methoxy-benzenesulfonamide and 3-ureidobenzene boronic acid, gave 5-formyl-6-methoxy-3′-ureido-biphenyl-3-sulfonamide.

출처 및 근거

ORD 기록: ord-29547db1d6ed4ec9b42a618b4fa50f01
출처 데이터셋: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08299110B2

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