3'-Amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide → 3'-amino-5-formyl-6-methoxy-N-(3-piperidin-3-ylpropanoyl)-biphenyl-3-sulfonamide

HRID 2069972노트

반응식

HRID 2069972 반응식
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:13]([O:14][CH3:15])=[C:12]([CH:16]=[O:17])[CH:11]=[C:10]([S:18]([NH2:21])(=[O:20])=[O:19])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[NH:22]1[CH2:27][CH2:26][CH2:25][CH:24]([CH2:28][CH2:29][C:30](Cl)=[O:31])[CH2:23]1>>[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[C:13]([O:14][CH3:15])=[C:12]([CH:16]=[O:17])[CH:11]=[C:10]([S:18]([NH:21][C:30](=[O:31])[CH2:29][CH2:28][CH:24]3[CH2:25][CH2:26][CH2:27][NH:22][CH2:23]3)(=[O:19])=[O:20])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 866077123'-Amino-5-formyl-6-methoxy-biphenyl-3-sulfonamideHCID 866077353-Piperidin-3-ylpropanoyl chloride

생성물 1

HCID 866077343'-amino-5-formyl-6-methoxy-N-(3-piperidin-3-ylpropanoyl)-biphenyl-3-sulfonamide

실험 절차

Proceeding as in Reference 21, but substituting 3′-amino-5-formyl-6-methoxy-biphenyl-3-sulfonamide and 3-piperidin-3-ylpropanoyl chloride, gave 3′-amino-5-formyl-6-methoxy-N-(3-piperidin-3-ylpropanoyl)-biphenyl-3-sulfonamide.

출처 및 근거

ORD 기록
ord-ef5763ade0164c6581021ee1dc85e046
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08299110B2

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