4-[4-(Methylamino)-3-nitrophenoxy]pyridine-2-carboxamide → 4-(3-Amino-4-(methylamino)phenoxy]pyridine-2-carboxamide
반응식
[CH3:1][NH:2][C:3]1[CH:18]=[CH:17][C:6]([O:7][C:8]2[CH:13]=[CH:12][N:11]=[C:10]([C:14]([NH2:16])=[O:15])[CH:9]=2)=[CH:5][C:4]=1[N+:19]([O-])=O>CO.[Pd]>[NH2:19][C:4]1[CH:5]=[C:6]([CH:17]=[CH:18][C:3]=1[NH:2][CH3:1])[O:7][C:8]1[CH:13]=[CH:12][N:11]=[C:10]([C:14]([NH2:16])=[O:15])[CH:9]=1참가 물질
4
실험 절차
The mixture containing 4-[4-(methylamino)-3-nitrophenoxy]pyridine-2-carboxamide in methanol with catalytic amount of 10% Pd/C was hydrogenated to yield 4-(3-amino-4-(methylamino)phenoxy]pyridine-2-carboxamide.
출처 및 근거
- ORD 기록
- ord-d8a1b9ccf1304174a5770f772489c449
- 출처 데이터셋
- uspto-grants-2012_10
- 특허 번호
- US08299108B2
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