Methyl 6-cyano-2-methylnicotinate → Methyl 6-(aminomethyl)-2-methylpyridine-3-carboxylate

반응식

[C:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[C:5]([CH3:13])[N:4]=1)#[N:2].C(C1C=C(CN)C=CN=1)(C)C>>[NH2:2][CH2:1][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[C:5]([CH3:13])[N:4]=1

참가 물질

반응물 2

HCID 55253164Methyl 6-cyano-2-methylnicotinate

HCID 59569820(2-Isopropylpyridin-4-yl)methanamine

생성물 1

HCID 59569936Methyl 6-(aminomethyl)-2-methylpyridine-3-carboxylate

실험 절차

methyl 6-(aminomethyl)-2-methylnicotinate was synthesized from methyl 6-cyano-2-methylnicotinate following the general procedure as described for 2-isopropyl-4-pyridylmethylamine.

출처 및 근거

ORD 기록: ord-3a905e998d024eec87b214273a9fc72e
출처 데이터셋: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08299267B2

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