Boc aminomethyl bromide → N-(3-cyano-5-(prop-1-en-2-yl)phenyl)methanesulfonamide

HRID 2070956노트

반응식

HRID 2070956 반응식
Br[C:2]1[CH:3]=[C:4]([NH:10][S:11]([CH3:14])(=[O:13])=[O:12])[CH:5]=[C:6]([C:8]#[N:9])[CH:7]=1.C(NCBr)(O[C:18](C)([CH3:20])[CH3:19])=O>>[C:8]([C:6]1[CH:5]=[C:4]([NH:10][S:11]([CH3:14])(=[O:13])=[O:12])[CH:3]=[C:2]([C:18]([CH3:20])=[CH2:19])[CH:7]=1)#[N:9]

참가 물질

3

반응물 2

HCID 20614913Boc aminomethyl bromideHCID 68670101N-(3-bromo-5-cyanophenyl)methanesulfonamide

생성물 1

HCID 68670071N-(3-cyano-5-(prop-1-en-2-yl)phenyl)methanesulfonamide

실험 절차

N-(3-cyano-5-(prop-1-en-2-yl)phenyl)methanesulfonamide was synthesized from N-(3-bromo-5-cyanophenyl)methanesulfonamide following the general procedure as described for the Cbz protected Boc aminomethyl bromide.

출처 및 근거

ORD 기록
ord-471d37889f23449cb1b269e3f32d2b1a
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08299267B2

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